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EXPLORER as a Transformational Imaging Technology for Drug Development

The development and commercialization of the EXPLORER PET scanner has paved a new way for conducting whole body clinical PET imaging studies. In comparison to other commercially available scanners, this highly sophisticated imaging technology offers 40X greater sensitivity to enhance the visualization of biological interactions across diverse disease indications. This massive increase in sensitivity can be used in a number of ways, including:

  • Performing scans at extremely low radiation doses (similar magnitude to the dose received from a round trip flight between San Francisco and London)
  • Performing scans much more quickly (potentially in less than a minute)
  • Tracking the fate of radiotracers for a much longer time after injection

This presentation will provide an overview of the technology, present early data and discuss its applications.


Speaker information below.



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About The Speakers

Simon R. cherry, ph.d.
Professor, Department of Biomedical Engineering and Department of Radiology, University of California, Davis

Dr. Simon R. Cherry is a Distinguished Professor at the University of California, Davis where he develops novel technologies and methods for quantitative biomedical imaging. His major accomplishments have been in developing and applying high-resolution systems for positron emission tomography (PET), particularly the invention of microPET technology, and co-leading the EXPLORER project, which recently has built the world's first total-body PET scanner.

Dr. Cherry is a founding member of the Society for Molecular Imaging and an elected fellow of six professional societies, including the Institute for Electronic and Electrical Engineers (IEEE) and the Biomedical Engineering Society (BMES). He is editor-in-chief of the journal Physics in Medicine and Biology. Dr. Cherry received the Academy of Molecular Imaging Distinguished Basic Scientist Award (2007), the Society for Molecular Imaging Achievement Award (2011), the IEEE Marie Sklodowska-Curie Award (2016) and the SNMMI Paul C. Aebersold Award (2018). In 2016, he was elected as a member of the National Academy of Engineering, and in 2017, he was elected to the National Academy of Inventors. Dr. Cherry has authored more than 200 peer-reviewed journal articles, review articles and book chapters in the field of biomedical imaging.

Dr. Cherry received his BSc (Hons) in physics with astronomy from the University College London in 1986 and his Ph.D. in medical physics from the Institute of Cancer Research, University of London, in 1989. After a postdoctoral fellowship at the University of California, Los Angeles (UCLA), he joined the faculty in the UCLA Department of Molecular and Medical Pharmacology in 1993. In 2001, Dr. Cherry joined UC Davis as a professor in the Department of Biomedical Engineering and established the Center for Molecular and Genomic Imaging, which he directed from 2004 to 2016. Currently, Dr. Cherry serves as Co-Director of the EXPLORER Molecular Imaging Center.

Roger Gunn, PH.D.
Chief Scientific Officer, Neuroscience, Invicro

Dr. Roger Gunn is an international expert on imaging for disease understanding and drug development. He has a Ph.D. in Applied Mathematics from Warwick University and has worked across Academia (Imperial College London, Oxford University & McGill University), Industry (GSK & Imanova) and Government Labs (MRC Cyclotron Unit). He has made significant contributions to the development of novel imaging biomarkers, quantitative algorithms and software for a wide range of imaging applications with a focus on the neurosciences. He currently holds professorships at Imperial College London and Oxford University and has 200 publications in the field of imaging.