Invicro’s Image analysis teams work hand-in-hand with sponsors to develop customized image analysis and processing workflows that help drive drug discovery and development across therapeutic areas and phases.

Brian Avants

Ph.D. | Senior Director, Machine Learning

Education: Ph.D. in Bioengineering, University of Pennsylvania

Years of Experience: 20+ years

Location: Boston, MA

As an interdisciplinary scientist with a focus on neuro MR, Dr. Brian Avants has broadly explored the synergies between machine learning, brain mapping and mathematical modeling. Dr. Avants utilizes this expertise in developing computational and algorithmic advances to enhance Invicro’s imaging and data analytics platform.


Chantal de Bakker

Chantal de Bakker

Ph.D. | Scientist I, Image Analysis

Lino Becerra

Ph.D. | Vice President, MRI

Education: Ph.D. in Physics, University of Illinois

Years of Experience: 25+ years

Location: Boston, MA

Dr. Lino Becerra serves as Vice President of MRI to further consolidate and expand Invicro's capabilities to support studies utilizing MRI techniques from preclinical to clinical trials. Previously, Dr. Becerra was the Co-Director for The Center for Pain and the Brain at Harvard Medical School as well as being a faculty member for over 20 years. He has worked extensively in neuroimaging applications in neurological conditions. He Co-Founded Descartes Therapeutics Inc., a biotech company that was dedicated to the development of drugs for chronic pain and was Co-Director of the Imaging Consortium for Drug Development, which was formed by Harvard, McLean Hospital, Massachusetts General Hospital, Merck, Eli Lilly and Sepracor Pharmaceuticals.

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Derek Cissell

VMD, Ph.D., DACVR | Director, Discovery Laboratory

Cristian Constantinescu

Ph.D. | Associate Director, Translational Research

Education: Ph.D. in Biomedical Engineering, Purdue University

Years of Experience: 14+ years

Location: New Haven, CT

Dr. Cristian Constantinescu has been with Invicro since 2014, serving as Associate Director of Translational Research, specializing in image analysis and kinetic modeling of PET\SPECT data as well as managing image analysis projects in non-human primates and early clinical space.


Howard Dobson

DV.Sc. | Senior Director, Discovery and Preclinical Services

DV.Sc. in Veterinary Radiology, University of Guelph

Location: Boston, MA

Years of Experience: 44+ years

Dr. Howard Dobson has a broad ranging career in imaging research, both as a clinical veterinary radiologist and has spent the last 15 years in contract research.


Zhen Fan

Ph.D. | Senior PET Modeller

Education: Ph.D. in PET Modelling and Neuroimaging, Imperial College London

Years of Experience: 10+ years

Location: London, UK

Dr. Zhen Fan works as a PET Modeller at Invicro, and prior, gained her Ph.D. in neuroimaging modelling while working as an imaging data researcher at Imperial College London. Dr. Fan has over 10 years of experience working with PET/MRI imaging analysis in human and preclinical trials. 

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Louise Fanchon

Ph.D. | Scientist II, Dosimetrist

Devan Fleury

Senior Scientist, Pathology Image Analysis

Leon Fonville

Ph.D. | Senior MRI Scientist

Omid Ghasemi

Ph.D. | Associate Director, Pathology Image Analysis

Education: Ph.D. in Electrical Engineering, The University of Texas

Location: Boston, MA

Years of Experience: 7+ years

Dr. Omid Ghasemi has 7+ years of research experience in imaging informatics and data analysis developing digital pathology pipelines for drug and biomarker development at different pharmaceutical companies. Currently, Dr. Ghasemi is leading efforts developing innovative image analysis applications across a wide breadth of Advanced Pathology Services projects.


Ali Ghayoor

Ph.D. | Senior Scientist, MRI & Software

Education: Ph.D. in Electrical and Computer Engineering, The University of Iowa

Years of Experience: 12+ years

Location: Boston, MA

Dr. Ali Ghayoor has a strong background in medical image analysis, machine learning and software engineering. Dr. Ghayoor's main focus is on the application of machine learning in automated image analysis, software support for Invicro's image analysis platform (VivoQuantTM), design and scientific support for the translational and clinical core lab workflows. 


Elliot Greenblatt

Ph.D. | Principal Scientist, Head of Advanced Special Projects

Education:  Ph.D. in Mechanical Engineering, Massachusetts Institute of Technology 

Years of Experience: 14+ years

Location:  Boston, MA

Dr. Greenblatt develops medical imaging software and hardware to guide drug development and therapy. In this work, he utilizes a range of machine learning algorithms to better understand medical images.

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Keryn Gresco

Associate Director, DPS Image Analysis

Education: Master's Degree in Biomedical Engineering, University of Vermont

Years of Experience: 8+ years

Location: Boston, MA



Roger Gunn

Ph.D. | Chief Scientific Officer

Education: Ph.D. in Applied Mathematics, Warwick University

Years of Experience:  30+ years

Location: London, UK

Dr. Roger Gunn is an international expert in PET neuroimaging with 30 years’ experience designing and analyzing imaging studies for disease understanding and drug development. Dr. Gunn is also a Professor of Molecular Neuroimaging at Imperial College London and has published over 200 peer-reviewed papers in the field of imaging with an H-Index of 65.


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Victoria hedges

Victoria Hegedus

Analysis Manager
Jack Heinann-1

Jack Heimann

Analysis Manager
Shianne Hunter

Shianne Hunter

Analysis Manager

Sven Macholl

Ph.D. | Director, Discovery Research, Europe

Education:  Ph.D. in Physical Chemistry, Freie Universität Berlin

Years of Experience: 15+ years

Location: London, UK

Dr. Sven Macholl studied Chemistry in Kiel, Germany while in parallel, worked in the marine chemistry lab of the local institute of marine sciences. Dr. Macholl specialized in physical chemistry/chemical physics for his diploma thesis performing microwave spectroscopy of small molecules using quantum mechanics for analysis. Dr. Macholl spent time in academia in Berlin, Magdeburg and St. Petersburg, Russia in the related fields of NMR spectroscopy, clinical MRS & fMRI and experimental low field MRI. Dr. Macholl later joined GE Healthcare in the UK to perform research in the novel Dissolution Dynamic Nuclear Polarization technique with one of its inventors. Having spent time alongside medicinal chemists and the radio nuclear imaging scientists at the site, he then decided to join the radio nuclear R&D team as a physicist/image analyst and preclinical lab scientist working with rodents. 

Dr. Macholl joined Invicro in 2014 performing and managing preclinical imaging projects across all major imaging modalities. Currently, he manages the contract research performed at academic preclinical partner labs, as well as working with the neuro-imaging team in the UK and supporting the various preclinical and translational U.S. teams.


Michael Maker

Senior Program Manager II, Image Analysis

Education: Masters of Science in Electrical and Computer Engineering Leadership, Northeastern University

Years of Experience: 11+ years

Location: Boston, MA

Mr. Michael Maker leads the Project Management teams across Software and Image Analysis. Previously, Mr. Maker worked in big pharma in preclinical, translational and clinical imaging labs.


Ryan Petrulli

Ph.D. | Associate Director, Image Analysis

Education: Ph.D. in Biomedical Engineering, Yale University

Years of Experience: 3+ years

Location:  New Haven, CT


Gaia Rizzo

Ph.D. | Associate Director, Oncology Image Analysis

Education: Ph.D. in Information Engineering/Specialization in Bioengineering, University of Padova

Years of Experience: 14+ years

Location:  London, UK

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Catarina Rua

Ph.D. | MR Physicist

Christine Sandiego

Ph.D. | Senior Scientist, Translational Research

Education: Ph.D. in Biomedical Engineering, Yale University

Years of Experience: 15+ years

Location: New Haven, CT

Dr. Christine Sandiego has been at Invicro since 2015 with expertise in kinetic modeling and analysis of positron emission tomography (PET) brain data. She is a scientific lead on the translational research team for pre-clinical and early clinical PET studies, helping to support our sponsors’ drug development programs for neurodegenerative diseases.

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Nicholas Santo

Analysis Manager

Graham Searle

Ph.D. | Head of PET Analysis

Education: Ph.D. in Mathematical Modelling, The University of Warwick

Years of Experience: 19+ years

Location: London, UK

Dr. Graham Searle has over 15 years of experience in the development and application of mathematical models for human imaging data. His career has focused on the use of PET imaging in drug development, and the development and implementation of tools for PET data analysis within the context of the pharmaceutical industry.


Matt Wall

Ph.D. | Senior Imaging Scientist

Education: Ph.D. in Cognitive and Brain Sciences, University of Cambridge

Years of Experience: 20+ years

Location: London, UK

Dr. Matt Wall earned his Ph.D.  in psychology with a post-doctoral focus in psychophysics. Dr. Wall's day-to-day work blends neuroscience and MRI methodology, with a specialty in pharmacology. 


Xue Wang

Ph.D. | Senior Scientist, MRI

Education: Ph.D. in Biomedical Engineering, University of Kentucky

Years of Experience: 15+ years

Location: Boston, MA



Alex Whittington

Alex Whittington

Ph.D. | Associate Director, IQ Analytics

Ken Zasadny

Ph.D. | Director, Research Programs & Translational Imaging

Education: Ph.D. in Nuclear Engineering, University of Michigan

Years of Experience: 31+ years

Location: Boston, MA

Dr. Ken Zasadny has a mix of academia and pharmaceutical industry experience. His career focus has been on quantitative molecular imaging by PET and SPECT for diagnostic and therapeutic applications.