Brian Avants
Ph.D. | Senior Director, Machine Learning
Education: Ph.D. in Bioengineering, University of Pennsylvania
Years of Experience: 20+ years
Location: Boston, MA
As an interdisciplinary scientist with a focus on neuro MR, Dr. Brian Avants has broadly explored the synergies between machine learning, brain mapping and mathematical modeling. Dr. Avants utilizes this expertise in developing computational and algorithmic advances to enhance Invicro’s imaging and data analytics platform.
Lino Becerra
Ph.D. | Vice President, MRI
Education: Ph.D. in Physics, University of Illinois
Years of Experience: 25+ years
Location: Boston, MA
Dr. Lino Becerra serves as Vice President of MRI to further consolidate and expand Invicro's capabilities to support studies utilizing MRI techniques from preclinical to clinical trials. Previously, Dr. Becerra was the Co-Director for The Center for Pain and the Brain at Harvard Medical School as well as being a faculty member for over 20 years. He has worked extensively in neuroimaging applications in neurological conditions. He Co-Founded Descartes Therapeutics Inc., a biotech company that was dedicated to the development of drugs for chronic pain and was Co-Director of the Imaging Consortium for Drug Development, which was formed by Harvard, McLean Hospital, Massachusetts General Hospital, Merck, Eli Lilly and Sepracor Pharmaceuticals.
Cristian Constantinescu
Ph.D. | Associate Director, Translational Research
Education: Ph.D. in Biomedical Engineering, Purdue University
Years of Experience: 14+ years
Location: New Haven, CT
Dr. Cristian Constantinescu has been with Invicro since 2014, serving as Associate Director of Translational Research, specializing in image analysis and kinetic modeling of PET\SPECT data as well as managing image analysis projects in non-human primates and early clinical space.
Howard Dobson
DV.Sc. | Senior Director, Discovery and Preclinical Services
Zhen Fan
Ph.D. | Senior PET Modeller
Education: Ph.D. in PET Modelling and Neuroimaging, Imperial College London
Years of Experience: 10+ years
Location: London, UK
Dr. Zhen Fan works as a PET Modeller at Invicro, and prior, gained her Ph.D. in neuroimaging modelling while working as an imaging data researcher at Imperial College London. Dr. Fan has over 10 years of experience working with PET/MRI imaging analysis in human and preclinical trials.
Omid Ghasemi
Ph.D. | Associate Director, Pathology Image Analysis
Education: Ph.D. in Electrical Engineering, The University of Texas
Location: Boston, MA
Years of Experience: 7+ years
Dr. Omid Ghasemi has 7+ years of research experience in imaging informatics and data analysis developing digital pathology pipelines for drug and biomarker development at different pharmaceutical companies. Currently, Dr. Ghasemi is leading efforts developing innovative image analysis applications across a wide breadth of Advanced Pathology Services projects.
Ali Ghayoor
Ph.D. | Senior Scientist, MRI & Software
Education: Ph.D. in Electrical and Computer Engineering, The University of Iowa
Years of Experience: 12+ years
Location: Boston, MA
Dr. Ali Ghayoor has a strong background in medical image analysis, machine learning and software engineering. Dr. Ghayoor's main focus is on the application of machine learning in automated image analysis, software support for Invicro's image analysis platform (VivoQuantTM), design and scientific support for the translational and clinical core lab workflows.
Elliot Greenblatt
Ph.D. | Principal Scientist, Head of Advanced Special Projects
Education: Ph.D. in Mechanical Engineering, Massachusetts Institute of Technology
Years of Experience: 14+ years
Location: Boston, MA
Dr. Greenblatt develops medical imaging software and hardware to guide drug development and therapy. In this work, he utilizes a range of machine learning algorithms to better understand medical images.
Keryn Gresco
Associate Director, DPS Image Analysis
Education: Master's Degree in Biomedical Engineering, University of Vermont
Years of Experience: 8+ years
Location: Boston, MA
Roger Gunn
Ph.D. | Chief Scientific Officer
Education: Ph.D. in Applied Mathematics, Warwick University
Years of Experience: 30+ years
Location: London, UK
Dr. Roger Gunn is an international expert in PET neuroimaging with 30 years’ experience designing and analyzing imaging studies for disease understanding and drug development. Dr. Gunn is also a Professor of Molecular Neuroimaging at Imperial College London and has published over 200 peer-reviewed papers in the field of imaging with an H-Index of 65.
Sven Macholl
Ph.D. | Director, Discovery Research, Europe
Education: Ph.D. in Physical Chemistry, Freie Universität Berlin
Years of Experience: 15+ years
Location: London, UK
Dr. Sven Macholl studied Chemistry in Kiel, Germany while in parallel, worked in the marine chemistry lab of the local institute of marine sciences. Dr. Macholl specialized in physical chemistry/chemical physics for his diploma thesis performing microwave spectroscopy of small molecules using quantum mechanics for analysis. Dr. Macholl spent time in academia in Berlin, Magdeburg and St. Petersburg, Russia in the related fields of NMR spectroscopy, clinical MRS & fMRI and experimental low field MRI. Dr. Macholl later joined GE Healthcare in the UK to perform research in the novel Dissolution Dynamic Nuclear Polarization technique with one of its inventors. Having spent time alongside medicinal chemists and the radio nuclear imaging scientists at the site, he then decided to join the radio nuclear R&D team as a physicist/image analyst and preclinical lab scientist working with rodents.
Dr. Macholl joined Invicro in 2014 performing and managing preclinical imaging projects across all major imaging modalities. Currently, he manages the contract research performed at academic preclinical partner labs, as well as working with the neuro-imaging team in the UK and supporting the various preclinical and translational U.S. teams.
Michael Maker
Senior Program Manager II, Image Analysis
Education: Masters of Science in Electrical and Computer Engineering Leadership, Northeastern University
Years of Experience: 11+ years
Location: Boston, MA
Mr. Michael Maker leads the Project Management teams across Software and Image Analysis. Previously, Mr. Maker worked in big pharma in preclinical, translational and clinical imaging labs.
Ryan Petrulli
Ph.D. | Associate Director, Image Analysis
Education: Ph.D. in Biomedical Engineering, Yale University
Years of Experience: 3+ years
Location: New Haven, CT
Gaia Rizzo
Ph.D. | Associate Director, Oncology Image Analysis
Education: Ph.D. in Information Engineering/Specialization in Bioengineering, University of Padova
Years of Experience: 14+ years
Location: London, UK
Christine Sandiego
Ph.D. | Senior Scientist, Translational Research
Education: Ph.D. in Biomedical Engineering, Yale University
Years of Experience: 15+ years
Location: New Haven, CT
Dr. Christine Sandiego has been at Invicro since 2015 with expertise in kinetic modeling and analysis of positron emission tomography (PET) brain data. She is a scientific lead on the translational research team for pre-clinical and early clinical PET studies, helping to support our sponsors’ drug development programs for neurodegenerative diseases.
Graham Searle
Ph.D. | Head of PET Analysis
Education: Ph.D. in Mathematical Modelling, The University of Warwick
Years of Experience: 19+ years
Location: London, UK
Dr. Graham Searle has over 15 years of experience in the development and application of mathematical models for human imaging data. His career has focused on the use of PET imaging in drug development, and the development and implementation of tools for PET data analysis within the context of the pharmaceutical industry.
Matt Wall
Ph.D. | Senior Imaging Scientist
Education: Ph.D. in Cognitive and Brain Sciences, University of Cambridge
Years of Experience: 20+ years
Location: London, UK
Dr. Matt Wall earned his Ph.D. in psychology with a post-doctoral focus in psychophysics. Dr. Wall's day-to-day work blends neuroscience and MRI methodology, with a specialty in pharmacology.
Xue Wang
Ph.D. | Senior Scientist, MRI
Education: Ph.D. in Biomedical Engineering, University of Kentucky
Years of Experience: 15+ years
Location: Boston, MA
Ken Zasadny
Ph.D. | Director, Research Programs & Translational Imaging
Education: Ph.D. in Nuclear Engineering, University of Michigan
Years of Experience: 31+ years
Location: Boston, MA
Dr. Ken Zasadny has a mix of academia and pharmaceutical industry experience. His career focus has been on quantitative molecular imaging by PET and SPECT for diagnostic and therapeutic applications.