Where does the drug go? And what does it do? In drug discovery these are two big questions that hold various challenges. In the case of gene therapy, researchers need to address these questions for both the gene-carrying particle and the gene itself which provides further complications.
In this webinar we will cover the challenges in answering these questions using current techniques and will introduce and demonstrate several multi-modality imaging approaches that addresses these challenges. These approaches, ranging from in vivo imaging to ex vivo tissue molecular imaging, provides a suite of comprehensive solutions to interrogate the bio-distribution, pharmacokinetics, pharmacodynamics and pharmacoexpression of the vector and the gene.
Dr. Bloom has more than 30 years of clinical experience and has been an early adopter of precision medicine. He is a renowned researcher and lecturer in pathology, cancer, telemedicine, and informatics.
Dr. Bloom recently joined Invicro as the CMO of advanced pathology and advanced genomic services. Prior to Invicro, he served as the President and head of oncology and immunotherapy at Human Longevity Inc., Chief Medical Officer of In Vitro Diagnostics at GE Healthcare, senior medical director at US Labs and director of laboratory operations at Rush Medical Center. Dr. Bloom has held a series of academic position as including Clinical Professor of Pathology at USC and CIO at Rush Cancer Center.
Matthew Silva, Ph.D., brings 16 years of diverse imaging experience from pharmaceutical and contract research organizations including 4 previous years at Invicro during which he helped build out the Boston lab. Most recently he was Senior Director of Translational Biology at Vertex Pharmaceuticals, where he ran the in vivo imaging and histopathology groups. Previously, Matt led imaging groups at Amgen, Millennium and Takeda Pharmaceuticals, during which he supported broad use of imaging biomarkers to support drug discovery and development. He holds a PhD and Masters in Biomedical Engineering from Worcester Polytechnic Institute. In his role as EVP of Scientific Applications, he will work across discovery, translational, and clinical projects providing scientific expertise with a focus outside of neuroscience and will assist in strengthening relationships in the pharmaceutical industry.